Studies in Microbic Dissociation

Dissociation of Microbic Species

Two types of organism have been shown to exist in cultures of the bacillus of rabbit septicemia, recently isolated from spontaneous infections. One, Microbe D, grows diffusely in serum and plain broth, forms rather opaque, fluorescing colonies on serum agar, and is highly virulent for rabbits. These characters are retained throughout many passages in serum or plain broth. The other type, Microb...

The Microbic Dissociation of Hemophilus Influenzae *

Dissociation in both pathogenic and non-pathogenic bacterial species has long attracted attention, both in this country and abroad, and, as a result, a voluminous literature on the subject has been accumulating. Since the work of Arkwright' and of deKruif7 in I921, dissociational variations in the properties within a bacterial species have been studied in a more or less systematic manner so tha...

Microbic Virulence and Host Susceptibility

One of us (Webster) has shown that the general non-specific resistance of mice bred at the Rockefeller Institute includes important elements associated with heredity and that, by selective breeding, the general resistance of a mouse population may be altered? We wish now to describe some experiments which demonstrate the effect of diet on host susceptibility to infection and intoxication. For s...

Studies of the Effect of Sodium Azide on Microbic Growth and Respiration: I. The Action of Sodium Azide on Microbic Growth.

In recent years, publications from this laboratory (Snyder and Lichstein, 1940; Lichstein and Snyder, 1941; Lichstein, 1941) have indicated the value of sodium azide (NaN3) as an aid in the isolation of streptococci from clinical material containing "spreaders" and other interfering gram-negative organisms. The use of blood-infusion agar containing 0.02 per cent sodium azide for the cultivation...

Microbic Decomposition of Pantothenic Acid.